Leading edge bioinformatics, molecular therapies and supercomputing


Download CCG Brochure


Latest Media

Professors Wilton and Fletcher


  • WA Innovator of the Year Research Scientists join the CCG Prominent molecular geneticists Professor Steve Wilton and Professor Sue Fletcher from the Australian Neuromuscular Research Institute have joined Murdoch University’s Centre for Comparative Genomics (CCG) to continue their award-winning research into therapies for rare diseases. more...
  • WA Scientists' research attracts worldwide licensing deal more...
  • Cloud Computing set to facilitate WA innovation LOCAL and national research projects will be able to scale up activities with the establishment of the iVEC NeCTAR Research Cloud infrastructure in Western Australia more...
  • Exciting new research by Dr Mike Bunce’s team and the CCG on the novel use of DNA to unravel the ingredients contained within Traditional Chinese Medicines (TCM). The research is published in the journal PLoS Genetics more...
iVEC@Murdoch Supercomputer Launch
  • iVEC@Murdoch launched at Murdoch University New supercomputer ranked 87th in the world (Top500.org) launched at Murdoch University. "The supercomputing facilities promote world class research into areas such as energy exploration and agriculture production that will greatly enhance our national prosperity and quality of life,” Senator Carr said. more...

View all media statements


Latest News


Building 390

  • New Staff The CCG welcomes new Software Developers, Rodney Lorrimar & Lee Render, to the team.
  • New Staff Professors Steve Wilton and Sue Fletcher have recently joined the CCG to continue their exciting research in Molecular Therapies. Professor Wilton has taken up the position of Foundation Chair in Molecular Therapies. Dr Amsha Nahid has recently joined the CCG to provide expert advice in metabolomic data analysis for therapy tracking.
  • Prof Matthew Bellgard has been awarded a 2012 short-term OECD Fellowship award from the Co-operative Research Programme in Biological Resource Management for Sustainable Agricultural Systems. He will reside at the National Center for Genome Resources, Santa Fe, New Mexico.
  • On May 7, Prof Alan Bittles book entitled 'Consanguinity in Context' will be published by Cambridge University Press, UK:more...
  • Upgrades to the BRL Display Wall are now complete. The nine HD projectors powering the display are now capable of higher contrast and better colour reproduction under varied lighting conditions. See pictures...
BRL Display Wall

View all news items


Latest Publications

  • Dáithí C. Murray, Stuart G. Pearson, Richard Fullagar, Brian M. Chase, Jayne Houston, Jenny Atchison, Nicole E. White, Matthew I. Bellgard, Edward Clarke, Mike Macphail, M. Thomas P. Gilbert, James Haile and Michael Bunce. High-throughput Sequencing of Ancient Plant and Mammal DNA in herbivore Middens. Quaternary Science Reviews (In press)
  • Rodrigues M, Hammond-Tooke G, Kidd A, Love D, Patel R, Dawkins H, Bellgard M, Roxburgh R. The New Zealand Neuromuscular Disease Registry. J Clin Neurosci. 2012Sep 18. pii: S0967-5868(12)00232-9. doi: 10.1016/j.jocn.2012.04.008. [Epub ahead of print] PubMed PMID: 22999565
  • Mappley LJ, Black ML, Abuoun M, Darby AC, Woodward MJ, Parkhill J, Turner AK, Bellgard MI, La T, Phillips ND, La Ragione RM, Hampson DJ. Comparative genomics of Brachyspira pilosicoli strains: genome rearrangements, reductions and correlation of genetic compliment with phenotypic diversity. BMC Genomics. 2012 Sep 5;13(1):454. [Epub ahead of print] PubMed PMID: 22947175 more...
  • McCooke JK, Appels R, Barrero RA, Ding A, Ozimek-Kulik JE, Bellgard MI, Morahan G, Phillips JK. A novel mutation causing nephronophthisis in the Lewis polycystic kidney rat localises to a conserved RCC1 domain in Nek8. BMC Genomics.2012 Aug 16;13:393. PubMed PMID: 22899815; PubMed Central PMCID: PMC3441220.more...
  • Webster H, Keeble G, Dell B, Fosu-Nyarko J, Mukai Y., Moolhuijzen P, Bellgard M, Jia J, Kong X, Feuillet C, Choulet F, Genome-level identification of cell wall invertase genes in wheat for the study of drought tolerance. Functional Plant Biology 39(7) 569-579 Pub: 12 July 2012 more...
  • Bellgard M, Macgregor A, Janon F, Harvey A, O'Leary P, Hunter A and Dawkins H, A modular approach to disease registry design: Successful adoption of an Internet-based rare disease registry. Human Mutation. 2012. more...
  • Edwards D, Wilcox S, Barrero RA, Fleury D, Cavanagh CR, Forrest KL, Hayden MJ, Moolhuijzen P, Keeble-Gagnère G, Bellgard MI, Lorenc MT, Shang CA, Baumann U, Taylor JM, Morell MK, Langridge P, Appels R, Fitzgerald A. Bread matters: a national initiative to profile the genetic diversity of Australian wheat. Plant Biotechnol J. 2012 Aug;10(6):703-708. doi: 10.1111/j.1467-7652.2012.00717.x. Epub2012 Jun 9. PubMed PMID: 22681313 more...
  • Black ML, Moolhuijzen P , Chapman B , Barrero B, Howieson J, Hungria M and Bellgard MI, The Genetics of Symbiotic Nitrogen Fixation: Comparative Genomics of 14 Rhizobia Strains by Resolution of Protein Clusters. Genes. 2012 Mar;3 (1): 138-166. doi: 10.3390/genes3010138
  • Coghlan ML, Haile J, Houston J, Murray DC, White NE, Moolhuijzen P, Bellgard MI, Bunce M. Deep sequencing of plant and animal DNA contained within traditional Chinese medicines reveals legality issues and health safety concerns. PLoS Genet. 2012 Apr;8(4):e1002657. Epub 2012 Apr 12. PubMed PMID: 22511890; PubMed Central PMCID: PMC3325194 more...
  • Lane A,E Black ML and Wyatt KM, Toxicity and efficacy of a novel doxorubicin and carboplatin chemotherapy protocol for the treatment of canine appendicular osteosarcoma following limb amputation. Aust Vet J. 2012 Mar; 90(3):69-74. doi: 10.1111/j.1751-0813.2011.00878.x. PubMed PMID: 22339117 more...
  • Appels R, Barrero R, Bellgard M. Advances in biotechnology and linking outputs to variation in complex traits: Plant and Animal Genome meeting January 2012. Funct Integr Genomics. 2012 Mar;12(1):1-9. Epub 2012 Feb 22 PubMed PMID: 22354577. more...
  • Hunter A, Macgregor B, Szabo T, Wellington C and Bellgard MI, Yabi: An online research environment for Grid, High Performance and Cloud computing, Source Code for Biology and Medicine 2012, 7:1 doi:10.1186/1751-0473-7-1 Published: 15 February 2012 more...
  • Bellgard MI, Moolhuijzen PM, Guerrero FD, Schibeci D, Rodriguez-Valle M, Peterson DG, Dowd SE, Barrero R, Hunter A, Miller RJ, Lew-Tabor AE. CattleTickBase: An integrated Internet-based bioinformatics resource for Rhipicephalus (Boophilus) microplus. Int J Parasitol. 2012 Feb;42(2):161-9. Epub 2011 Dec 1. PubMed PMID: 22178513. more... GoTo Cattletickbase
  • Barrero R, Chapman B, Yang Y, Moolhuijzen P, Keeble-Gagnere G, Zhang N, Tang Q, Bellgard MI and Qiu D, De novo assembly of Euphorbia fischeriana root transcriptome identifies prostratin pathway related genes, BMC Genomics 2011, 12:600 doi:10.1186/1471-2164-12-600 Published: 13 December 2011more...
  • Taniya T, Tanaka S, Yamaguchi-Kabata Y, Hanaoka H, Yamasaki C, Maekawa H,Barrero RA, Lenhard B, Datta MW, Shimoyama M, Bumgarner R, Chakraborty R,Hopkinson I, Jia L, Hide W, Auffray C, Minoshima S, Imanishi T, Gojobori T. A prioritization analysis of disease association by data-mining of functional annotation of human genes. Genomics. 2011 Oct 14. PubMed PMID: 22019378.more...
  • Bellgard MI, Bellgard SE. A bioinformatics framework for plant pathologists to deliver global food security outcomes Accepted: 12 October 2011 Australasian Plant Pathology Society Inc. 2011 more...
  • Murray DC, Bunce M, Cannell BL, Oliver R, Houston J, White NE, Barrero RA, Bellgard MI, Haile J. DNA-Based Faecal Dietary Analysis: A Comparison of qPCR and High Throughput Sequencing Approaches. PLoS One. 2011;6(10):e25776. Epub 2011 Oct 6. PubMed PMID: 21998697; PubMed Central PMCID: PMC3188572. more...
  • Zheng, W, Peng, Y, Ma J, Appels R, Sun D, Ma W.High frequency of abnormal high molecular weight glutenin alleles in Chinese wheat landraces of the Yangtze-River region. Journal of Cereal Science (Article in Press) Aug 2011 more...
  • Diepeveen D, Clarke G.P.Y., Ryan K, Tarr A, Ma W, Appels R, Molecular genetic mapping of NIR spectra variation. The Journal of Cereal Science (2011), July 2011 doi:10.1016/j.jcs.2011.07.007 [Ahead of Print]
  • Sinha S, Black ML, Agarwal S, Das R, Bittles AH, Bellgard M. ThalInd, a β-thalassemia and hemoglobinopathies database for India: defining a model country-specific and disease-centric bioinformatics resource. Hum Mutat. 2011 Aug;32(8):887-93. doi: 10.1002/humu.21510. Epub 2011 Jun 23. PubMed PMID: 21520336.more...
  • Bittles AH. Assessing the influence of consanguinity on congenital heart disease. Ann Pediatr Cardiol. 2011 Jul;4(2):111-6. PubMed PMID: 21976867;PubMed Central PMCID: PMC3180965.more...
  • Gao L, Yan X, Li X, Guo G, Hu Y, Ma W, Yan Y. Proteome analysis of wheat leaf under salt stress by two-dimensional difference gel electrophoresis (2D-DIGE). Phytochemistry. 2011 Jul;72(10):1180-91. Epub 2011 Jan 21. PubMed PMID: 21257186.more...
  • Roessner U, Nahid A, Chapman B, Hunter A, and Bellgard M .Systems Biology Metabolomics – The Combination of Analytical Biochemistry, Biology, and Informatics. In: Murray Moo-Young (ed.), Comprehensive Biotechnology, Second Edition, volume 1, pp. 447–459. Elsevier. (In Print - July 2011)
  • Ghamkhar K, Isobe S, Nichols P, Faithfull T, Ryan M, Snowball R, Sato S, Appels R, The first genetic maps for subterranean clover (Trifolium subterraneum L.) and comparative genomics with T. pratense L. and Medicago truncatula Gaertn. to identify new molecular markers for breeding. Molecular Breeding. (Article in Press).
  • Moolhuijzen P, Lew-Tabor A, Morgan J, Valle M, Peterson D, Dowd S, Guerrero F, Bellgard MI, Appels R. The complexity of Rhipicephalus (Boophilus) microplus genome characterised through detailed analysis of two BAC Clones. more...
  • Barrero RA, Keeble-Gagnère G, Bing Zhang B, Moolhuijzen P,Kazuho Ikeo, Yoshio Tateno, Takashi Gojobori, Guerrero F, Lew-Tabor A, Bellgard MI. Evolutionary conserved microRNAs are ubiquitously expressed compared to tick-specific miRNAs in the cattle tick Rhipicephalus (Boophilus) microplus.BMC Genomics. 2011; 12: Published online 2011 June 24. doi: 10.1186/1471-2164-12-328. more...
  • Bittles AH. Time to get real: investigating potential beneficial genetic aspects of consanguinity. Public Health Genomics. 2011;14(3):169-71; discussion 172. Epub 2010 Dec 10. PubMed PMID: 21150169. more...
  • Islam S, Ma W, Yan G, Gao L, Appels R. Differential recovery of lupin proteins from the gluten matrix in lupin-wheat bread as revealed by mass spectrometry and two-dimensional electrophoresis. J Agric Food Chem. 2011 Jun 22;59(12):6696-704.Epub 2011 May 24. PubMed PMID: 21548652. more...
  • Lew-Tabor AE, Kurscheid S, Barrero R, Gondro C, Moolhuijzen PM, Rodriguez Valle M, Morgan JA, Covacin C, Bellgard MI. Gene expression evidence for off-target effects caused by RNA interference-mediated gene silencing of Ubiquitin-63E in the cattle tick Rhipicephalus microplus. Int J Parasitol. 2011 Jun 15. [Epub ahead of print] PubMed PMID: 21712043. more...
  • Zou Z, Hu H, Song M, Shen Y, Guo X, McElreavey K, Bittles AH, Wang W. Semen quality analysis of military personnel from six geographical areas of the People's Republic of China. Fertil Steril. 2011 May;95(6):2018-23, 2023.e1-3. Epub 2011 Mar 27. PubMed PMID: 21444069.more...
  • Hamamy H, Antonarakis SE, Cavalli-Sforza LL, Temtamy S, Romeo G, Ten Kate LP,Bennett RL, Shaw A, Megarbane A, van Duijn C, Bathija H, Fokstuen S, Engel E, Zlotogora J, Dermitzakis E, Bottani A, Dahoun S, Morris MA, Arsenault S, Aglan MS, Ajaz M, Alkalamchi A, Alnaqeb D, Alwasiyah MK, Anwer N, Awwad R, Bonnefin M,Corry P, Gwanmesia L, Karbani GA, Mostafavi M, Pippucci T, Ranza-Boscardin E,Reversade B, Sharif SM, Teeuw ME, Bittles AH. Consanguineous marriages, pearls and perils: Geneva International Consanguinity Workshop Report. Genet Med. 2011 May 6. [Epub ahead of print] PubMed PMID: 21555946. more...
  • Egerbladh I, Bittles AH. Socioeconomic, demographic and legal influences on consanguinity and kinship in northern coastal sweden 1780-1899. J Biosoc Sci. 2011 Jul;43(4):413-35. Epub 2011 Mar 22. PubMed PMID: 21418728. more...
  • Sun Y, He Z, Ma W, Xia X. Alternative splicing in the coding region of Ppo-A1 directly influences the polyphenol oxidase activity in common wheat (Triticum aestivum L.). Funct Integr Genomics. 2011 Mar;11(1):85-93. Epub 2010 Nov 3. PubMed PMID: 21046181.more...
  • She M, Ye X, Yan Y, Howit C, Belgard M, Ma W. Gene networks in the synthesis and deposition of protein polymers during grain development of wheat. Funct Integr Genomics. 2011 Mar;11(1):23-35. Epub 2010 Oct 20. Review. PubMed PMID: 20960020.more...
  • La T, Phillips ND, Wanchanthuek P, Bellgard MI, O'Hara AJ, Hampson DJ. Evidence that the 36kb plasmid of Brachyspira hyodysenteriae contributes to virulence. Vet Microbiol. 2011 Mar 3. [Epub ahead of print] PubMed PMID: 21458173.more...
  • Jin X, Harasymow S, Bonnardeaux Y, Tarr A, Appels R, Lance R, Zhang G LiC QTLs for malting flavour component associated with pre-harvest sprouting susceptibility in barley (Hordeum vulgare L.)Journal of Cereal Science Volume 53, Issue 2, March 2011, Pages 149-153. more...
  • Wang K, Gao L, Wang S, Zhang Y, Li X, Zhang M, Xie Z, Yan Y, Belgard M, Ma W. Phylogenetic relationship of a new class of LMW-GS genes in the M genome of Aegilops comosa. Theor Appl Genet. 2011 May;122(7):1411-25. Epub 2011 Feb 8. PubMed PMID: 21301802. more...
  • Appels R, Adelson DL, Moolhuijzen P, Webster H, Barrero R, Bellgard M. Genome studies at the PAG 2011 conference. Funct Integr Genomics. 2011 Mar 1. [Epub ahead of print] PubMed PMID: 21360134. more...
  • Barrero RA, Bellgard M, Zhang X. Diverse approaches to achieving grain yield in wheat. Funct Integr Genomics. 2011 Jan 8.[Epub ahead of print] PubMed PMID: 21221697. more...
  • Mago R, Simkova H, Brown-Guedira G, Dreisigacker S, Breen J, Jin Y, Singh R,Appels R, Lagudah ES, Ellis J, Dolezel J, Spielmeyer W. Erratum to: An accurate DNA marker assay for stem rust resistance gene Sr2 in wheat. Theor Appl Genet. 2010 Dec 24. [Epub ahead of print] PubMed PMID: 21184047. more...


View all Publications